Search: Germany; Department of Biochemistry | Frontiers in Life Science

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Found 2 articles for "Germany; Department of Biochemistry"

Vol. 20, Issue 1 2026 ID: a4ULT

Elucidating the Allosteric Mechanisms in Human AMPK Through High-Resolution Cryo-EM Studies

Hans-Peter Müller, Li Ming-Hu, Priya N. Iyer

The allosteric regulation of AMP-activated protein kinase (AMPK) plays a pivotal role in cellular energy homeostasis, making it a critical target for therapeutic intervention in metabolic disorders. Despite extensive study, the detailed structural me...

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Vol. 19, Issue 10 2025 ID: F8Xvk

Elucidating the Role of snRNA Modifications in Pre-mRNA Splicing Efficiency

Hannes F. Müller, Aditi R. Nair, Zhang Min-Jie

The intricate process of RNA splicing is crucial for the generation of mature messenger RNA (mRNA), yet the influence of small nuclear RNA (snRNA) modifications on splicing efficiency remains poorly understood. This study aims to explore the impact o...

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Elucidating the Allosteric Mechanisms in Human AMPK Through High-Resolution Cryo-EM Studies

Elucidating the Role of snRNA Modifications in Pre-mRNA Splicing Efficiency